Theoretical and Uniaxial Experimental Evaluation of Human Annulus Fibrosus Degeneration
نویسندگان
چکیده
منابع مشابه
Theoretical and uniaxial experimental evaluation of human annulus fibrosus degeneration.
The highly organized structure and composition of the annulus fibrosus provides the tissue with mechanical behaviors that include anisotropy and nonlinearity. Mathematical models are necessary to interpret and elucidate the meaning of directly measured mechanical properties and to understand the structure-function relationships of the tissue components, namely, the fibers and extrafibrillar mat...
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The annulus fibrosus (AF) of the intervertebral disc experiences cyclic tensile loading in vivo at various states of mechanical equilibrium. Disc degeneration is associated with alterations in the biochemical composition of the AF including decreased water content, decreased proteoglycan concentration, and increased collagen deposition that affect mechanical function of the AF in compression an...
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STUDY DESIGN Biomechanical testing of partially nucleotomized ovine cadaveric spines. OBJECTIVE To explore how the nucleus pulposus (NP) affects the biomechanical behavior of the intervertebral disc (IVD) by performing a partial nucleotomy via the transpedicular approach. SUMMARY OF BACKGROUND DATA Mechanical loading represents a crucial part of IVD homeostasis. However, traditional regener...
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There is a critical need for tissue engineered replacements for diseased and degenerated intervertebral discs in order to assuage low back pain while restoring function to the spine. Despite progress by many research groups, it remains a challenge to engineer a replacement tissue that can withstand the complex, demanding loading environment of the spine. Due to the hierarchical organization of ...
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C ALCIUM deposition in diseased heart valves may be demonstrated frequently in necropsy studies, but these deposits are usually overlooked clinicaIIy unless the heart is carefuIly examined roentgenographically. Sosman1 discusses in detail a simple method of demonstrating the presence of calcific deposits within the heart by x-ray. He suggests a small fluoroscopic aperture and a screen of high i...
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ژورنال
عنوان ژورنال: Journal of Biomechanical Engineering
سال: 2009
ISSN: 0148-0731,1528-8951
DOI: 10.1115/1.3212104